While celebrating their last night together, Jo and Raissa stumble upon a mysterious portal that transports them to the fantastical island of Nakali, packed with magical and mythological creatures they grew up hearing stories about from their Filipino families.

Some of these figures will become friends, some foes. Joined by well-meaning-but- hapless weredog Raww (Dave Franco) and a small-but-mighty pack of pals, Jo and Raissa must face The Dreaded Manananggal (Tony winning icon Lea Salonga), the most feared creature on the island. When they discover that the memories of their entire friendship are the price for returning home, Jo and Raissa will race to find a way to leave the island before they forget each other forever.